Publications

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2009年度

15

創薬バリューチェインのインシリコ技術を活用した阻害剤開発の試み.

井上豪、松村浩由、安達宏昭、森勇介、高野和文、村上聡、福西快文、中村春木、木下誉富、仲西功、奥野泰史、南方聖司、三上義明、佐久間俊広、北島正人、福岡良忠、高田俊和、坂田恒昭

日本結晶学会誌 52(1),84-94 (2010). 2010.3

13

Enhancement of femtosecond laser-induced nucleation of protein in a gel solution.

Ryota Murai, Hiroshi Y. Yoshikawa , Yoshinori Takahashi , Mihoko Maruyama , Shigeru Sugiyama , Gen Sazaki , Hiroaki Adachi , Kazufumi Takano , Hiroyoshi Matsumura, Satoshi Murakami , Tsuyoshi Inoue , Yusuke Mori

Appl. Phys. Lett. 96,43702 (2010). 2010.3

12

Remarkable emissions in diprotonated 2,2’:6’2”-terpyridine derivatives.

Naokazu Yoshikawa, Shinichi Yamabe, Nobuko Kanehisa, Tsuyoshi Inoue, Hiroshi Takashima, and Keiichi Tsukahara

J. Phys. Org. Chem. 23,431-439 (2010). 2010.2

11

Crystal Structure of Peroxiredoxin from Aeropyrum pernix K1 Complexed with its Substrate, Hydrogen Peroxide.

Tsutomu Nakamura, Yuji Kado, Takafumi Yamaguchi, Hiroyoshi Matsumura, Kazuhiko Ishikawa and Tsuyoshi Inoue

J. Biochem 147,109-115 (2010). 2010.1

10

Femtosecond laser processing of protein crystals grown in agarose gel.

Hitoshi Hasenaka, Shigeru Sugiyama, Mika Hirose, Noriko Shimizu, Tomoya Kitatani, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, and Hiroyoshi Matsumura

J. Cryst. Growth 312,73-78 (2009). 2009.12

9

Promotion of crystal nucleation of protein by semi-solid agarose gel.

Kana Tanabe, Mika Hirose, Ryota Murai, Shigeru Sugiyama, Noriko Shimizu, Mihoko Maruyama, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yusuke Mori, Eiichi Mizohata, Tsuyoshi Inoue, and Hiroyoshi Matsumura

Appl. Phys. Express 2,125501 (2009). 2009.12

8

Structural basis of interprotein electron transfer for nitrite reduction in denitrification.

Masaki Nojiri, Hiroyasu Koteishi, Takuya Nakagami, Kazuo Kobayashi, Tsuyoshi Inoue, Kazuya Yamaguchi and Shinnichiro Suzuki

Nature 462,117-120 (2009). 2009.11

7

Growth of large protein crystals by top-seeded solution growth together with floating and aolution-stirring technique.

Noriko Shimizu, Shigeru Sugiyama, Mihoko Maruyama, Hiroshi Y. Yoshikawa, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Hiroyoshi Matsumura and Yusuke Mori

Cryst. Growth Des 9, 5227-5232 (2009). 2009.11

6

A Manipulating Tool for Protein Microcrystals in Solution using Adhesive Materials.

T. Kitatani, H. Adachi, S. Sugiyama, H. Matsumura, R. Murai, Y. Takahashi, S. Murakami, T. Inoue, Y. Mori, and K. Takano

Jpn. J. Appl. Phys. 48, 11801 (2009). 2009.11

5

Requirement of a Unique Ca2+-Binding Loop for Folding of Tk-subtilisin from a Hyperthermophilic Archaeon.

Yuki Takeuchi, Shun-ichi Tanaka, Hiyroyoshi Matsumura, Yuichi Koga, Kazufumi Takano, and Shigenori Kanaya

Biochemistry 48, 10637-10643 (2009). 2009.10

4

Femtosecond Laser Processing of Agarose Gel Surrounding Protein Crystals for the development of an Automated Crystal Capturing System.

Shigeru Sugiyama, Hitoshi Hasenaka, Mika Hirose, Tomoya Kitatani, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yusuke Mori, Tsuyoshi Inoue, and Hiroyoshi Matsumura

Jpn. J. Appl. Phys. 48105502-1-105502-5 (2009). 2009.10

3

Crystal structure of the apo, decarbamylated form of 2,3-diketo-5-methylthiopentyl-1-phosphate enolase from Bacillus subtilis.

Haruka Tamura, Yohtaro Saito, Hiroki Ashida, Yasushi Kai, Tsuyoshi Inoue, Akiho Yokota, and Hiroyoshi Matsumura

Acta Cryst. D65 9, 942-951 (2009). 2009.9

2

Protein crystallization in agarose gel with high strength: Developing an automated system for protein crystallographic processes.

Shigeru Sugiyama, Kana Tanabe, Mika Hirose, Tomoya Kitatani, Hitoshi Hasenaka, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yusuke Mori, Tsuyoshi Inoue, and Hiroyoshi Matsumura

Jpn. J. Appl. Phys. 48, 75502-1-75502-5 (2009). 2009.7

1

Mechanistic insights into the hydrolysis and synthesis of ceramide by neutral ceramidase.

Tsuyoshi Inoue, Nozomu Okino, Yoshimitsu Kakuta, Atsushi Hijikata, Hiroyuki Okano, Hatsumi M. Goda, Motohiro Tani, Noriyuki Sueyoshi, Koji Kambayashi, Hiroyoshi Matsumura, Yasushi Kai, and Makoto Ito

J. Biol. Chem. 284(14), 9566-9577 (2009). 2009.4